The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 33036-62-3, name is 4-Bromo-1-butanol. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 33036-62-3
Preparation 9 1-Tetrahydropyranyloxy-4-bromobutane (Formula XXIII: A is trimethylene). Concentrated hydrobromic acid (75 drops of 48%) is added with stirring to a mixture of 4-bromobutanol (150 ml.) and dihydropyran (300 ml.) at 0. This mixture is stirred and allowed to warm slowly to 25 C. during 15 hours. Evaporation under reduced pressure gives a residue which is divided into two equal parts, each part being chromatographed on 1.5 kg. of silica gel, each column being eluted with 7.5 l. of 5% ethyl acetate in Skellysolve B, and then with 4 l. of 7.5% ethyl acetate in Skellysolve B, collecting 500 ml. fractions. Fractions 5-11 from each column are evaporated to give a total of 240 g. of 1-tetrahydropyranyloxy-4-bromobutane.
With the rapid development of chemical substances, we look forward to future research findings about 33036-62-3.
Reference:
Patent; The Upjohn Company; US3983154; (1976); A;,
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