Application of 60666-70-8, Adding some certain compound to certain chemical reactions, such as: 60666-70-8, name is (2-Bromo-5-chlorophenyl)methanol,molecular formula is C7H6BrClO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 60666-70-8.
Add compound 3 (500 mg, 2.26 mmol) in DCM (40 mL) and DIPEA (1.12 mL, 6.77 mmol)DMAP (55.16 mg, 451.51 mumol) was added. Then, pivaloyl chloride (416.65 uL, 3.39 mmol) was added dropwise at 0 ° C to react.The mixture was stirred at 10 ° C for 0.1 hour and then at room temperature overnight. The reaction mixture was diluted with DCM and then usedWater, 10percent citric acid and brine were washed with MgSO4 and filtered. The filtrate was concentrated to give a crude product which was purified by CC.The compound 4 (605 mg, 87.69percent) was obtained as a pale yellow oil.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 60666-70-8, (2-Bromo-5-chlorophenyl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Chinese Academy Of Sciences Tianjin Industry Bio-technology Institute; Lin Jianping; Liu Pi; Li Jinlong; Wang Zhonghua; Liu Cui; (15 pag.)CN108264467; (2018); A;,
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