In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 456-47-3 as follows., 456-47-3
General procedure: Alcohol (1 mmol), water (1 mL), and CoFe2O4 MNPs (11.8mg, 5 mol %) were added to a round-bottomed flask. The reaction mixture was stirred for the two minutes, and then oxone (0.6 mmol) was added in three portions. The reaction mixture was placed at room temperature and stirred for the specified time (Table 5). The reaction was followed by TLC (EtOAc-cyclohexane, 2:10). After the completion of the reaction, the product was extracted in dichloromethane. The solvent was evaporated under reduced pressure to give the corresponding aromatic products. Purification of the residue using plate chromatography (silica gel) provided the pure carbonyl compounds. The aliphatic products in dichloromethane was dried with anhydrous MgSO4 and detected by GC-FID.
The chemical industry reduces the impact on the environment during synthesis 456-47-3, I believe this compound will play a more active role in future production and life.
Reference:
Article; Sadri, Fariba; Ramazani, Ali; Massoudi, Abdolhossain; Khoobi, Mehdi; Azizkhani, Vahid; Tarasi, Roghayeh; Dolatyari, Leila; Min, Bong-Ki; Bulletin of the Korean Chemical Society; vol. 35; 7; (2014); p. 2029 – 2032;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts