Analyzing the synthesis route of 1-(2,6-Dichloro-3-fluorophenyl)ethanol

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 756520-66-8, 1-(2,6-Dichloro-3-fluorophenyl)ethanol, other downstream synthetic routes, hurry up and to see.

Electric Literature of 756520-66-8, Adding some certain compound to certain chemical reactions, such as: 756520-66-8, name is 1-(2,6-Dichloro-3-fluorophenyl)ethanol,molecular formula is C8H7Cl2FO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 756520-66-8.

To a stirred mixture of D8 (65.5mg, 0.43mmol) and A5 (81mg, 0.39mmol) in THF (5mL), was added Ph3P (152mg, 0.58mmol) under the protection of nitrogen. After being stirred at r.t. for Ih, the mixture was added DIAD (1 17mg, 0.58mmol) at 00C. The resulting mixture was stirred at r.t. for two days and evaporated. The residue was purified by column chromatography (PE:EA=20: l) to afford D9 (1 13mg, 86%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 756520-66-8, 1-(2,6-Dichloro-3-fluorophenyl)ethanol, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; XCOVERY, INC.; WO2008/88881; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts