As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 647-42-7, name is 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, molecular formula is C8H5F13O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Application In Synthesis of 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol
(3) In a 4-liter reactor equipped with electromagnetic stirring, a rectification column, a thermometer, a constant pressure dropping funnel, a separator, a condenser, etc., 2500 g of an intermediate product obtained by (2) (6.05 mol of a fluorine-containing alcohol) is added. 20 g of p-toluenesulfonic acid and 13 g of hydroquinone. StirThe temperature was raised to 90 C, and 413 g (5.74 mol) of acrylic acid was added dropwise thereto for 2 hours.At the end of the reaction, no significant water droplets were produced after 5 hours of continuous reaction.The fluorine-containing olefin and the unreacted fluoroalcohol are distilled off.Refining 2133 g of perfluorohexylethyl acrylate, the purity is 99.02%,The yield was 88.8%.
With the rapid development of chemical substances, we look forward to future research findings about 647-42-7.
Reference:
Patent; Jinan Qifu New Materials Co., Ltd.; Shandong Chemical Institute; Li Haijing; Zhang Liting; (6 pag.)CN108911983; (2018); A;,
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