Electric Literature of 2043-47-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.2043-47-2, name is 1H,1H,2H,2H-Nonafluoro-1-hexanol, molecular formula is C6H5F9O, molecular weight is 264.0889, as common compound, the synthetic route is as follows.
Example 3In a 200-ml, three-necked glass reactor were placed 80 ml of methylene chloride, 10 g (38 mmol) of 3,3,4,4,5,5,6,6,6-nonafluorohexanol, 5 g (58 mmol) of methacrylic acid, 10 g (57 mmol) of benzenesulfonic acid chloride and 0.1 g of a polymerization inhibitor, Sumilizer GM. While the reaction temperature was kept at 40 C. or lower, 12 g (119 mmol) of triethylamine was added dropwise. After the completion of the dropwise addition, stirring was conducted at room temperature for 1 hour. At this point, the conversion was 99% and the selectivity was 99%.
Statistics shows that 2043-47-2 is playing an increasingly important role. we look forward to future research findings about 1H,1H,2H,2H-Nonafluoro-1-hexanol.
Reference:
Patent; TOKUYAMA CORPORATION; DAIKIN INDUSTRIES, LTD.; US2009/23948; (2009); A1;,
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