Brief introduction of Benzyl 2-hydroxyacetate

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Related Products of 30379-58-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 30379-58-9, name is Benzyl 2-hydroxyacetate, molecular formula is C9H10O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: The benzyl glycolate or thiobenzyl glycolate (1.5 equivalent) was added to the stirred suspension of peracetobromo-alpha-D-glucose, mannose, galactose (1 equivalent) and indium tribromide (10-15 mol%) in anhydrous dichloromethane (2 mL) at room temperature for an hour. The progress of reaction was monitored with thin layer chromatography. After the completion of the reaction, the reaction mixture was diluted with water and quenched with 10% aqueous acidic acid solution (1 mL). The organic layer washed with water and brine, the solvent was evaporated under reduced pressure and the crude product was purified by flash column chromatography on silica gel (90% ethyl acetate/hexanes). The corresponding beta-carboxymethyl glucosides (beta-CMGL) were afforded in good yield with high anomeric selectivity.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 30379-58-9, Benzyl 2-hydroxyacetate.

Reference:
Article; Chandra, Sunena; Yadav, Ram N.; Paniagua, Armando; Banik, Bimal K.; Tetrahedron Letters; vol. 57; 13; (2016); p. 1425 – 1429;,
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