Related Products of 2240-88-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 2240-88-2, name is 3,3,3-Trifluoropropan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.
Example 19 3-[(4-Methoxyphenyl)amino]-4-phenyl-1-(3, 3, 3-TRIFLUOROPROPYL)-LH-PYRROLE-2, 5-dione To a solution of 3-[(4-methoxyphenyl)amino]-4-phenyl-1H-pyrrole-2, 5-dione (0.17 mmol, 50 mg), 3,3, 3-TRIFLUOROPROPAN-1-OL (0.19 mmol, 21 mg), diethyl azodicarboxylate (0.19 mmol, 33 mg) in dry THF (1 ML) was added triphenylphosphine (0.19 mmol, 49 mg) in dry THF (1 mL). The mixture was heated in a microwave reactor at 130°C for six min.. After cooling, the reaction mixture was purified by HPLC (95percent 0. 1M ammonium acetate buffer: 5percent CH3CN X 100percent CH3CN) to give 51 mg (77percent) of the title COMPOUND. 1H NMR (400 MHz, CDCl3) 8 7.27 (bs, 1H), 7.17-7. 06 (m, 3H), 7.00-6. 95 (m, 2H), 6.64-6. 55 (M, 4H), 3. 89 (t, J=7.3 Hz, 2H), 3.70 (s, 3H), 2.61-2. 48 (M, 2H).
According to the analysis of related databases, 2240-88-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ASTRAZENECA AB; WO2005/5417; (2005); A1;,
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