Adding a certain compound to certain chemical reactions, such as: 112513-79-8, 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Quality Control of 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol, blongs to alcohols-buliding-blocks compound. Quality Control of 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol
A solution of racemic 6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol (30 mg), isopropenyl acetate (24-240 mul, 1-30 eq.) and NOV435 (30 mg) in 3.0 mL of solvent (toluene, acetonitrile, tetrahydrofuran or terc-buthyl methyl ester) was stirred gently at 35 C for 7 h in a 4 mL vial. Samples were collected after 3 and 7 h and were directly analyzed by chiral GC for ee of the product and reagent. Conversion (C) was calculated as C = eer/(eer + eep) and enantiomeric ratio (E) was calculated as E = ln[1 – C(1 + eep)]/ln[1 – C(1 – eep)].
The synthetic route of 112513-79-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; De Miranda, Amanda S.; Gomes, Juliana C.; Rodrigues Jr., Manoel T.; Costa, Ingrid C.R.; Almeida, Wanda P.; Lopes, Raquel De O.; Miranda, Leandro S.M.; Coelho, Fernando; De Souza, Rodrigo O.M.A.; Journal of Molecular Catalysis B: Enzymatic; vol. 91; (2013); p. 77 – 80;,
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