The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 116-02-9, name is 3,3,5-Trimethylcyclohexanol. This compound has unique chemical properties. The synthetic route is as follows. HPLC of Formula: C9H18O
a) 426g (3,00 Mol) of Homomenthol is added to the above-mentioned filtrate, the temperature is raised to 60C and under stirring and a vacuum of lOOmbar the Ethyl acetate is distilled off the reaction mixture. Then 56g of Sulfuric acid are added at a tempera- ture of 50C within 20minutes, stirring is continued for 6h. For work-up 500g of Toluene are added to the reaction mixture and after cooling to 5-10C the dosage of 500g of iced water follows. After separation of the water layer the organic layer is washed to neutral with aqueous Sodium hydroxide solution (10% w/w) and finally with saturated aqueous Sodium chloride solution. After separation of the water layer the organic layer is distilled resulting 250g (0,93 Mol) of product. Yield (overall): 58% of theory.
With the rapid development of chemical substances, we look forward to future research findings about 116-02-9.
Reference:
Patent; SYMRISE AG; STUHLMANN, Dominik; MEYER, Imke; KOCH, Oskar; OERTLING, Helko; HERRMANN, Martina; GOeMANN, Claudia; WO2014/198602; (2014); A1;,
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