Brief introduction of Trichloroethanol

The synthetic route of 115-20-8 has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 115-20-8, Trichloroethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C2H3Cl3O, blongs to alcohols-buliding-blocks compound. Formula: C2H3Cl3O

4.2.2.14 3,17beta-dimethoxy-17alpha-[2′,2′,2′-trichloroethyl-1′-N-tosylacetimidate]estra-1,3,5(10)-triene (4w) The general procedure was followed using 3,17beta-dimethoxy-17alpha-ethynyl-estra-1,3,5(10)-triene 1f and 2,2,2-trichloroethanol 3l, affording compound 4w (76 mg, 59%) as a white solid, mp 68-70 C, [alpha]D26 = +24 (? 0.98, CHCl3).

The synthetic route of 115-20-8 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Volkova, Yulia A.; Kozlov, Andrey S.; Kolokolova, Marya K.; Uvarov, Denis Y.; Gorbatov, Sergey A.; Andreeva, Olga E.; Scherbakov, Alexander M.; Zavarzin, Igor V.; European Journal of Medicinal Chemistry; vol. 179; (2019); p. 694 – 706;,
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