The origin of a common compound about 110-73-6

According to the analysis of related databases, 110-73-6, the application of this compound in the production field has become more and more popular.

Application of 110-73-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 110-73-6, name is 2-(Ethylamino)ethanol. This compound has unique chemical properties. The synthetic route is as follows.

Potassium carbonate (10.4 g, 75.4 mmol) and 2-(ethylamino)ethanol (6.72 g, 75.4 mmol) were added to a solution of 2-bromo-1-phenylethanone (5.00 g, 25.1 mmol) in acetonitrile (150 ml), and the mixture was stirred at RT overnight. The solids were then removed by filtration, and the filtrate was concentrated under reduced pressure to afford the crude title compound which was used in the next step without further purification. Yield: 5.00 g (85% purity, 82% yield). LC/MS [Method 3]: Rt = 0.44 min; MS (ESIpos): m/z = 208 [M+H]+. 1H-NMR (400 MHz, DMSO-d6): d [ppm] = 7.55-7.48 (m, 2H), 7.37-7.23 (m, 3H), 4.11-4.03 (m, 1H), 3.67-3.59 (m, 1H), 3.48-3.36 (m, 1H), 2.76-2.67 (m, 2H), 2.36-2.26 (m, 1H), 2.16-2.06 (m, 1H), 2.01 (d, 1H), 0.99 (t, 3H).

According to the analysis of related databases, 110-73-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; MUeLLER, Steffen; SCHOHE-LOOP, Rudolf; ORTEGA, HERNANDEZ, Nuria; SUeSSMEIER, Frank; JIMENEZ NUNEZ, Eloisa; BRUMBY, Thomas; LINDNER, Niels; GERDES, Christoph; POOK, Elisabeth; BUCHMUeLLER, Anja; GAUGAZ, Fabienne, Zdenka; LANG, Dieter; ZIMMERMANN, Stefanie; EHRMANN, Alexander, Helmut, Michael; GERISCH, Michael; LEHMANN, Lutz; TIMMERMANN, Andreas; SCHAeFER, Martina; SCHMIDT, Georg; SCHLEMMER, Karl-Heinz; FOLLMANN, Markus; KERSTEN, Elisabeth; WANG, Vivian; GAO, Xiang; WANG, Yafeng; (801 pag.)WO2019/219517; (2019); A1;,
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