Adding a certain compound to certain chemical reactions, such as: 623-50-7, Ethyl 2-hydroxyacetate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 623-50-7, blongs to alcohols-buliding-blocks compound. 623-50-7
To a stirred mixture of the pyridine 51a (2.00 g, 1.0 eq), the alcohol 51b (1.43 mL, 1.05 eq), CuI (0.05 g, 0.02 eq) is added Cs2CO3 (10.3 g, 2.2 eq) and heated at 70 C. during4 h. The reaction mixture is cooled down to RT, poured into H2O (300 mL) and allowed to stand for 1 h until precipitation. The suspension is filtered, triturated with Et2O/Hex (1:1), dried with toluene azeotrope to give 51c (2.0 g, 70%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,623-50-7, its application will become more common.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; US2010/261714; (2010); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts