Kolcsar, Vanessza Judit et al. published their research in ChemCatChem in 2022 | CAS: 120121-01-9

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol

Mechanochemical, Water-Assisted Asymmetric Transfer Hydrogenation of Ketones Using Ruthenium Catalyst was written by Kolcsar, Vanessza Judit;Szollosi, Gyorgy. And the article was included in ChemCatChem in 2022.Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol This article mentions the following:

The aim of this study was to develop a green system for the asym. transfer hydrogenation of ketones RC(O)R1 (R = Ph, 2,6-difluorophenyl, 4-methoxyphenyl, phenylethyl, etc.; R1 = Me) applying chiral Ru catalyst I in aqueous media and mechanochem. energy transmission. Using a ball mill, the milling parameters were optimized in the transfer hydrogenation of acetophenone followed by reduction of various substituted derivatives The scope of the method was extended to carbo- II (R2 = H, 5-OMe, 7-Br, 6-CF3, etc.; n = 1, 2, 3) and heterocyclic ketones III (R3 = H, 6-Cl, 8-Br; X = O, S, NH, N-BOC). The scale-up of the developed system was successful, and the optically enriched alcs. (R)-RC(OH)R1, IV, V could be obtained in high yields. The developed mechanochem. system provides TOFs up to 168 h-1. The present study is the first in which mechanochem. activated enantioselective transfer hydrogenations were carried out, thus, may be a useful guide for the practical synthesis of optically pure chiral secondary alcs. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol).

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts