Efficacy of supercritical carbon dioxide integrated hydrothermal extraction of Khmer medicinal plants with potential pharmaceutical activity was written by Chhouk, Kimthet;Wahyudiono;Kanda, Hideki;Goto, Motonobu. And the article was included in Journal of Environmental Chemical Engineering in 2018.Electric Literature of C10H22O3 This article mentions the following:
Khmer medicinal plants have been employed to treat human diseases for nearly a thousand years. Several studies have shown that the principal phytochem. constituents of such medicinal plants are phenolic acids, flavonoids, tannins, and alkaloids, which possess diverse bioactivities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, antiallergic, and antimicrobial. In the present study, the extraction of the phytochem. constituents of Khmer medicinal plants (Dialium cochinchinense Pierre, Cinnamomum cambodianum Lecomte, Gardenia angkorensis Pitard, Cananga latifolia (Hook.f. & Thomson) Finet & Gagnep, and Oroxylum indicum (L.) Kurz bark) is performed using a supercritical carbon dioxide integrated hydrothermal process (SC-CO2-H) at a temperature of 150°C, pressure of 10MPa, water flow rate of 2mL/min, CO2 flow rate of 0.15mL/min, and extraction time of 4h. The total phenolic compounds content and antioxidant activity of the Khmer medicinal plants were determined by using the Folin-Ciocalteu and DPPH scavenging activity methods, resp. The phytochem. constituents of such plants were identified using GC-MS anal. The results showed that the extracts obtained by SC-CO2-H contained a high amount of total phenolic compounds with potential antioxidant activity. The GC-MS results also suggested that the Khmer medicinal plants contained many bioactive compounds with a broad range of biol. activities, which could be employed in the food, pharmaceutical, and cosmetic industries. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Electric Literature of C10H22O3).
rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C10H22O3
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