Integrating the rapid constituent profiling strategy and multivariate statistical analysis for herb ingredients research, with Chinese official rhubarb and Tibetan rhubarb as an example was written by Luo, Dewei;He, Mingzhen;Li, Junmao;Du, Hui;Mao, Qiping;Pei, Na;Zhong, Guoyue;Ouyang, Hui;Yang, Shiling;Feng, Yulin. And the article was included in Arabian Journal of Chemistry in 2021.Recommanded Product: (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol This article mentions the following:
The Chinese official rhubarb (COR), from the genus Rheum, is listed in the Chinese Pharmacopoeia, while many rhubarb plant sources include in the Tibetan rhubarb (TR) are not attributable to Chinese Pharmacopoeia. Tibetan rhubarb is widely used as a natural medicine in Tibet; however, the difference in plant endogenous phytochems. between the COR and TR remains largely unclear.To establish a method for evaluating the chem. composition and metabolic difference between COR and TR.Using UHPLC-QTOF-MS/MS, we established a strategy to quickly and comprehensively identify the chem. components of COR and TR. Furthermore, multivariate statistical anal. was applied to identify the significant metabolic differences between the two.In total, 209 chem. compounds, including 51 anthraquinones, 44 stilbenes, 26 tannins, 52 acyl glycosides, and 36 other compounds, were identified using the data mining strategy. Importantly, 47 compounds may be the potential new compounds, while 35 significant metabolic differences were revealed between COR and TR.This study offers significant insight into the chem. composition and differences between COR and TR that could be used to develop their varieties and clin. applications. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6Recommanded Product: (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol).
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