Severe bullous allergic contact dermatitis caused by glycidyl methacrylate and other acrylates was written by Vogel, Tatiana Alexandra;Christoffers, Wietske Andrea;Engfeldt, Malin;Bruze, Magnus;Coenraads, Pieter-Jan;Schuttelaar, Marie-Louise Anna. And the article was included in Contact Dermatitis in 2014.Product Details of 4074-88-8 This article mentions the following:
A research illustrates a rarer case of a severe allergic contact dermatitis caused by acrylates glycidyl methacrylate and 1,6 hexanediol diacrylate in an occupational setting. The multiple reactivity to various acrylates in this patient can be explained by two different phenomena: cross-reactivity, and sub sequent exposure to other acrylates. This case report reveals the importance of patch testing with a dilution series of acrylates to distinguish between a contact allergy and an irritant reaction. And moreover, it emphasizes the importance of investigating the products in a patient’s workplace and testing the purity of these products. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Product Details of 4074-88-8).
Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 4074-88-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts