Optimisation of microwave-assisted extraction and functional elucidation of bioactive compounds from Cola nitida pod was written by Olalere, Olusegun Abayomi;Gan, Chee-Yuen;Akintomiwa, Olumide Esan;Adeyi, Oladayo;Adeyi, Abiola. And the article was included in Phytochemical Analysis in 2021.HPLC of Formula: 10083-24-6 This article mentions the following:
The quality characteristics and stability of phenolic byproducts from Cola nitida wastes are critical factors for drug formulation and food nutraceutical applications. In this study, the effect of electromagnetic-based microwave-reflux extraction on the total phenolic content, antioxidant capacity, morphol. characteristics, physisorption and chromatog. phenolic profiles were successfully investigated. These physicochem. analyses are often employed in the standardisation of dried herbal and food nutraceutical products. In this study, the electromagnetic-based extraction process was optimized using the Box-Behnken design. The oleoresin bio-products were subsequently characterised to determine the total phenolic content, morphol. and microstructural degradation These analyses were conducted to elucidate the effect of the microwave heating on the C. nitida pod powder. From the predicted response, the optimal percentage yield was achieved at 26.20% under 5.39 min of irradiation time, 440 W microwave power and oven temperature of 55°C. Moreover, the rapid estimation of the phenolic content and antioxidant capacity were recorded at 124.84 ± 0.064 mg gallic acid equivalent (GAE)/g dry weight (d.w.) and 6.93 ± 0.34μg/mL, resp. The physicochem. characterization results from the Fourier-transform IR spectroscopy, field emission SEM and physisorption analyses showed remarkable changes in the micro-surface area (13.66%) characteristics. The recorded optimal conditions established a basis for future scale-up of microwave extraction parameters with a potential for maximum yield. The physiochem. characterization revealed the functional characteristics of C. nitida and their tolerance to microwave heating. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6HPLC of Formula: 10083-24-6).
(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.HPLC of Formula: 10083-24-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts