Inhibition of cholesterol biosynthesis promotes the production of 1-octen-3-ol through mevalonic acid was written by Jin, Yuxi;Yuan, Xiaoya;Liu, Jianfeng;Wen, Jie;Cui, Huanxian;Zhao, Guiping. And the article was included in Food Research International in 2022.COA of Formula: C8H16O This article mentions the following:
1-Octen-3-ol makes an important contribution to meat flavor. The goal of this study was to identify the metabolic pathways of 1-octen-3-ol formation in meat. We found 218 metabolites associated with 1-octen-3-ol content in 20 samples of chicken meat, including mevalonic acid (pos. correlation), corticosterone (neg. correlation), and other lipids and lipid-like mols. Among these 218 metabolites, 17 metabolites were differentially expressed in different 1-octen-3-ol content groups. Similarly, 37 genes were not only differentially expressed, but were significantly correlated with 1-octen-3-ol. The regulation of HSP90AA1, PTPN9, and other genes converted more mevalonic acid to 1-octen-3-ol. Meanwhile, mevalonic acid, a key material in the synthesis of cholesterol, caused a decrease in corticosterone content, affecting ZNF414 and KLF15 gene expression. These findings reveal the effect of cholesterol on 1-octen-3-ol content, as well as a pos. regulation of mevalonic acid on the production of 1-octen-3-ol in chicken meat. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4COA of Formula: C8H16O).
Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C8H16O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts