New chiral metal cluster systems for catalytic asymmetric syntheses of chiral alcohols was written by Li, Yan-yun;Chen, Jian-shan;Yang, Chuan-bo;Dong, Zhen-rong;Li, Bao-zhu;Zhang, Hui;Gao, Jing-xing;Takao, Ikariya. And the article was included in Chemical Research in Chinese Universities in 2004.Name: (R)-1-(3-Chlorophenyl)ethanol This article mentions the following:
Efficient chiral Ru3(CO)12 systems were prepared in situ from Ru3(CO)12 and various chiral diimino- or diamino-diphosphine tetradentate ligands ((S,S)- and (R,R)-1,2-bis[[[2-(diphenylphosphino)phenyl]methylene]amino]cyclohexane, -1,2-bis[[[2-(diphenylphosphino)phenyl]methyl]amino]cyclohexane, -2-Ph2PC6H4CH:NCHPhCHPhN:CHC6H4PPh2-2 and -2-Ph2PC6H4CH2NHCHPhCHPhNHCH2C6H4PPh2-2), the preparation of which is described. The systems were used for the asym. transfer hydrogenation of propiophenone in iso-PrOH, leading to 1-phenyl-1-propanol in a 98% yield and 96% ee. The IR study suggests that the carbonyl hydride anion [HRu3(CO)11]– most probably exists as a principal species under the reaction conditions. The high chiral efficiency may be due to the synergetic effect produced by the neighboring Ru atoms and a special chiral micro-environment involving the polydentate ligand and the Ru3 framework. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Name: (R)-1-(3-Chlorophenyl)ethanol).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Name: (R)-1-(3-Chlorophenyl)ethanol
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