Direct and indirect eluates from bulk fill resin-based-composites was written by Durner, Juergen;Schrickel, Klaus;Watts, David C.;Becker, Marc;Draenert, Miriam E.. And the article was included in Dental Materials in 2022.SDS of cas: 109-17-1 This article mentions the following:
To compare elutable substances directly released from bulk-fill (BF) resin-based composites (RBCs) with indirect elution from teeth restored with a BF composite. In addition to (co)monomers, the anal. focus was on other potentially toxic ingredients or impurities. Furthermore, the barrier function of the residual dentin/adhesive layer was studied.Six BF-RBC materials were studied. For each material subgroup, ten human third molar teeth with standard Class-I occlusal cavities were prepared and provided with a three-step adhesive system and the resp. composite restoration (tooth groups). Same sized control specimens of the restorative material were prepared (′direct BF-RBC′ groups). Each specimen was placed in an elution chamber such that the elution media (ethanol/water, 3:1) only contacted the tooth root or 3/4 height of each specimen. They were incubated at 37 °C for up to 7 d. Samples of eluate were taken after 1, 2, 4 and 7 d and were analyzed by high-temperature gas chromatog./mass spectrometry.(Co)monomers such as Bisphenol A ethoxylate dimethacrylate (bisEMA) or tetraethylene glycol dimethacrylate (TEEGDMA) were mostly found in the eluates of the ′direct BF-RBC′ groups in statistically significantly greater amounts than in the eluates of the ′tooth groups′. The residual dentin and/or adhesive layers acted as a diffusion barrier for most of the substances except for triethylene glycol dimethacrylate (TEGDMA) or diethylene glycol dimethacrylate (DEGDMA). For TEGDMA up to 3 orders of magnitude more were found in the ′tooth groups′ compared to the ′direct BF-RBC′ groups, evidently released by the adhesive system.Substances of Very High Concern (SVHC) including TINUVIN 328 and BPA were found mainly in the eluates of ′direct BF-RBC′ groups.For estimation of biocompatibility, a total system, specifically BF-RBC + adhesive, should always be investigated since individual considerations, such as only elution from a BF-RBC, do not correctly reflect the total clin. situation. The focus of elution tests should not only be on the co(monomers), but also on other ingredients or impurities that may be released. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1SDS of cas: 109-17-1).
((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 109-17-1
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts