Metabolomics analysis of freeze-thaw tolerance enhancement mechanism of ε-poly-L-lysine on industrial yeast was written by Lu, Lu;Zhu, Ke-Xue;Yang, Zhen;Guo, Xiao-Na;Xing, Jun-Jie. And the article was included in Food Chemistry in 2022.Name: (2R,3S)-rel-Butane-1,2,3,4-tetraol This article mentions the following:
Antimicrobial polycationic peptide ε-poly-L-lysine (ε-PL) enhanced the freeze-thaw tolerance of industrial yeast; the enhancement mechanism of ε-PL on yeast was studied. The results showed that a ε-PL coating was observed in ε-PL-treated yeast. After 4 times of freeze-thaw, the cell viability, glycerol content, and CO2 production of 0.6 mg/mL ε-PL-treated yeast were higher than those of untreated yeast, specifically, the cell viability of ε-PL-treated yeast was 87.6%, and that of untreated yeast was 68.5%. Metabolomic results showed that the enhancement mechanism of ε-PL on yeast was related to the promotion of cell membrane-related fatty acid synthesis pathways before freeze-thaw treatment, and the promotion of biosynthesis and glycerophospholipid metabolism pathways after freeze-thaw. Furthermore, ε-PL induced inhibition of the tricarboxylic acid cycle, resulting in a longer stationary phase at the beginning of the freeze-thaw and ultimately providing a higher level of freeze-thaw stress tolerance than untreated yeast. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Name: (2R,3S)-rel-Butane-1,2,3,4-tetraol).
(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Name: (2R,3S)-rel-Butane-1,2,3,4-tetraol
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Alcohols – Chemistry LibreTexts