The reactions of pyridils and related compounds with alkali. II. The reactivities of several pyridils was written by Oda, Daihei. And the article was included in Nippon Kagaku Zasshi in 1961.Related Products of 1122-71-0 This article mentions the following:
Several diketones were prepared and their reactivities to alkali compared. 3-Pyridyl 3-picolyl ketone (10 g.) in 50 cc. dioxane oxidized with 8.4 g. SeO2 5 hrs. gave 6.6 g. 3,3′-pyridil (VII), m. 79-80°. 4-Pyridinecarboxaldehyde was treated with KCN to give 25% 4,4′-pyridoin, m. 165-7°, which was oxidized with HNO3 to give 4,4′-pyridil (VIII), m. 179-70.5°. Similarly, 2-pyridinecarboxaldehyde N-oxide gave 2,2′-pyridoin N,N-dioxide, m. 152-3° (decomposition), which was oxidized to yield 2,2′-pyridil N,N’-dioxide (IX), decomposed at 240-5°. Oxidation of 2-pyridyl 3-picolyl ketone with SeO2 yielded 2,3′-pyridil (X), m. 96-8°. 6,6′-Dimethyl-2,2′-pyridil (4.8 g.) treated with KOH as in the preceding part gave 2.8 g. 6-methylpicolinic acid, 0.08 g. 6-methyl-2-pyridylcarbinol, 0.4 g. 6,6′-dimethyl-2,2′-pyridoin, 0.15 g. NH3, and 0.4 g. unidentified carbonyl compound VII gave di-βpyridylglycolic acid, which was oxidized to nicotinic acid (XI) and di-β-pyridyl ketone, m. 105-7°. VIII (2.1 g.) gave 0.95 g. isonicotinic acid, 0.06 g. γ-pyridylcarbinol, and 0.06 g. NH3. X (2.1 g.) gave 0.8 g. XI, 0.05 g. NH3, 0.03 g. III, and 0.27 g. IV. IX (4.9 g.) gave 3.2 g. di-α-pyridylcarbinol N-oxide, m. 148-9°, and 0.22 g. IV. The results indicated that low electron density on the 2- or 4-position was the cause of abnormal reaction. The idea was supported by the results on IX. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Related Products of 1122-71-0).
6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 1122-71-0
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts