Chemoselective Cleavage of Si-C(sp3) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate) was written by Matsuoka, Keitaro;Komami, Narumi;Kojima, Masahiro;Mita, Tsuyoshi;Suzuki, Kimichi;Maeda, Satoshi;Yoshino, Tatsuhiko;Matsunaga, Shigeki. And the article was included in Journal of the American Chemical Society in 2021.Related Products of 2968-93-6 This article mentions the following:
Herein chemoselective cleavage of Si-C(sp3) bonds of unactivated tetraalkylsilanes was reported using iodine tris(trifluoroacetate). The reaction proceeded smoothly under mild conditions (-50°C to room temperature) and tolerated various polar functional groups, thus enabling subsequent Tamao-Fleming oxidation to provide the corresponding alcs. NMR experiments and d. functional theory calculations on the reaction indicated that the transfer of alkyl groups from Si to the I(III) center and the formation of the Si-O bond proceed concertedly to afford an alkyl-λ3-iodane and silyl trifluoroacetate. The developed method enabled the use of unactivated tetraalkylsilanes as highly stable synthetic precursors. In the experiment, the researchers used many compounds, for example, 2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6Related Products of 2968-93-6).
2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 2968-93-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts