New paracyclophane phosphine for highly enantioselective ruthenium-catalyzed hydrogenation of prochiral ketones was written by Cheemala, Murthy N.;Gayral, Maud;Brown, John M.;Rossen, Kai;Knochel, Paul. And the article was included in Synthesis in 2007.Recommanded Product: (R)-1-(3-Chlorophenyl)ethanol This article mentions the following:
A new unsym. (R)-Phanephos analog, [2.2]paracyclophane diphosphine (R)-(C2H4)2(1,4-C6H3-2-PAr2)(1,4-C6H3-3-PPh2) (2, Ar = 3,5-Me2C6H3) was prepared and tested as ligand for ruthenium-catalyzed asym. hydrogenation of acetophenones. Acetophenones XC6H4COMe were hydrogenated into the corresponding (αR)-α-methylbenzenemethanols by [(L2)RuCl2(H2NCR1R2CR2R1NH2)] (6a,b; R1, R2 = H, Ph; L2 = 2) with 94-97% ee. The ligand 2 was highly efficient in the ruthenium-catalyzed asym. hydrogenation of various aromatic and heteroaromatic ketones. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Recommanded Product: (R)-1-(3-Chlorophenyl)ethanol).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Recommanded Product: (R)-1-(3-Chlorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts