Enantioselective dialkylzinc addition to aldehydes catalyzed by chiral Zn(II)-BINOLates bearing phosphonates and phosphoramides in the 3,3′-positions was written by Hatano, Manabu;Miyamoto, Takashi;Ishihara, Kazuaki. And the article was included in Synlett in 2006.HPLC of Formula: 120121-01-9 This article mentions the following:
Highly enantioselective dialkylzinc addition to a series of aldehydes was developed based on chiral Zn(II)-BINOLate catalysts bearing phosphonates [P(:O)(OR)2] and phosphoramides [P(:O)(NMe2)2] at the 3,3′-positions. The reactions proceeded smoothly and showed reductions in the amounts of both catalysts and dialkylzinc reagents to be loaded. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9HPLC of Formula: 120121-01-9).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.HPLC of Formula: 120121-01-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts