Diarylmethane synthesis through Re2O7-catalyzed bimolecular dehydrative Friedel-Crafts reactions was written by Qin, Qi;Xie, Youwei;Floreancig, Paul E.. And the article was included in Chemical Science in 2018.HPLC of Formula: 220227-37-2 This article mentions the following:
The application of Re2O7 for the synthesis of diarylmethanes from benzylic alcs. through solvolysis followed by Friedel-Crafts alkylation was described. The reactions were characterized by broad substrate scope, low catalyst loadings, high chem. yields and minimal waste generation. The intermediate perrhenate esters were superior leaving groups to chlorides and bromides in these reactions. The polarity and water sequestering capacity of hexafluoroisopropyl alc. were critical to the success of these processes. Re2O7 was a precatalyst for HOReO3, which served as a less costly and easily handled promoter for these reactions. Oxorhenium catalysts selectively activate alcs. in the presence of similarly substituted acetates, indicating a unique chemoselectivity and mechanism in comparison to Bronsted acid catalysis. In the experiment, the researchers used many compounds, for example, (3,4,5-Trifluorophenyl)methanol (cas: 220227-37-2HPLC of Formula: 220227-37-2).
(3,4,5-Trifluorophenyl)methanol (cas: 220227-37-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 220227-37-2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts