Stereodynamic Chemosensor with Selective Circular Dichroism and Fluorescence Readout for in Situ Determination of Absolute Configuration, Enantiomeric Excess, and Concentration of Chiral Compounds was written by Bentley, Keith W.;Wolf, Christian. And the article was included in Journal of the American Chemical Society in 2013.Formula: C4H11NO This article mentions the following:
A stereodynamic chemosensor, 1-(4′-pyridyl)-8-(3′-formyl-4′-hydroxyphenyl)naphthalene N-oxide, having a parallel arrangement of a substrate-binding salicylaldehyde unit and an adjacent pyridyl N-oxide fluorophore undergoes rapid condensation with chiral amino alcs. and subsequent asym. transformation of the 1st kind toward a single rotamer. Crystallog. anal. shows that the concomitant central-to-axial chirality imprinting is controlled by minimization of steric repulsion and by intramol. hydrogen bonding between the bound amino alc. and the proximate N-oxide group. The substrate binding event results in strong CD effects and characteristic fluorescence changes which can be used for instantaneous in situ determination of the absolute configuration, enantiomeric composition and total concentration of a variety of chiral amino alcs. This chemosensing approach avoids time-consuming workup and purification steps, and it is applicable to minute sample amounts which reduces the use of solvents and limits waste production In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Formula: C4H11NO).
(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Formula: C4H11NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts