Intramolecular Pd-Catalyzed Reductive Amination of Enolizable sp3-C-H Bonds was written by Ford, Russell L.;Alt, Isabel;Jana, Navendu;Driver, Tom G.. And the article was included in Organic Letters in 2019.Recommanded Product: (3-Methyl-2-nitrophenyl)methanol This article mentions the following:
A palladium-catalyzed reductive cyclization of nitroarenes has been designed to construct sp3-C-NHAr bonds from sp3-C-H bonds by using an enolizable nucleophile to intercept a nitrosoarene intermediate. Exposure of ortho-substituted nitroarenes to 5 mol % of Pd(OAc)2 and 10 mol % of phenanthroline under 2 atm of CO constructs partially saturated 5-, 6-, or 7-membered N-heterocycles I (R1 = H, Cl, Me, etc.; R2 = H, F, Me, etc.; R3 = H, Me) using α-pyridyl carboxylates, malonates, 1,3-dimethylbarbituric acid, 1,3-diones, or difurans as the nucleophile. In the experiment, the researchers used many compounds, for example, (3-Methyl-2-nitrophenyl)methanol (cas: 80866-76-8Recommanded Product: (3-Methyl-2-nitrophenyl)methanol).
(3-Methyl-2-nitrophenyl)methanol (cas: 80866-76-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: (3-Methyl-2-nitrophenyl)methanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts