(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Electric Literature of C6H14O6
Plant gums of the genus Khaya. Structure of Khaya grandifolia gum was written by Aspinall, G. O.;Hirst, E. L.;Matheson, N. K.. And the article was included in Journal of the Chemical Society in 1956.Electric Literature of C6H14O6 This article mentions the following:
The gum was dissolved in 4% aqueous NaOH, precipitated several times with EtOH, dissolved in dilute HCl, precipitated with EtOH, and reprecipitated from H2O with (Me)2CO, yielding a white amorphous powder (I), [α]D18 122° (c 1.88, H2O); found: equivalent 344 (titration), uronic anhydride 47.2% (decarboxylation), and OMe 1.0%. Hydrolysis of I with N H2SO4 at 100° for 6 hrs. showed galactose 16.1, rhamnose 8.2, and arabinose <1%. Oxidation of I with HNO3 showed 58% of galactose and (or) galactouronic acid residues. Partial hydrolysis of 10 g. of I and fractionation on cellulose gave 0.37 g. L-rhamnose hydrate (II), m. 95°, [α]D17 9.8° (c 4.44, H2O), 0.023 g. L-arabinose (III), m. 155°, [α]D17 104°, 1.80 g. D-galactose (IV), m. 164°, [α]D18 81°, and Ba salts (V) of acid material. V was left in 4% methanolic HCl overnight, refluxed 7 hrs., neutralized with Ag2CO3, reduced with KBH4, deionized, hydrolyzed with N H2SO4 at 100° for 18 hrs., and chromatographed, giving II, 4-O-methylglucose, glucose (trace), and IV. V, 4.0 g., was absorbed on Amberlite IRA-400 (OAc form) and eluded with increasing concentrations of HOAc to give 6 fractions: Fraction 1, 0.172 g. sirup, was acid hydrolyzed and showed II and IV, and IV only after oxidation with Br-H2O. Fraction 2, 0.731 g. sirup, was acid hydrolyzed, showing II, III, IV, 4-O-methylglucuronic acid, and galacturonic acid; methylation, reduction with LiAlH4, methylation, hydrolysis, and separation of the sirup on cellulose gave 2,3,4,6-tetra-O-methyl-D-glucose, m. 84°, [α]D17 82° (c 1.12, H2O), 2,3,4,6-tetra-O-methyl-D-galactose (VI), [α]D18 97° (c 1.32, H2O), aniline derivative m. 194°, 3,4-di-O-methyl-L-rhamnose (VII), [α]D17 20° (c 1.42, H2O), 1,5-lactone derivative m. 80°, 2,3,6-tri-O-methyl-D-galactose (VIII), [α]D18 88° (c 0.5, H2O), 1,4-lactone derivative m. 96°. Fraction 3, 61 mg. sirup, was hydrolyzed, giving II and IV. Fraction 4, 0.102 g. sirup, contained D-galacturonic acid, converted into mucic acid, m. 220° (decomposition). Fraction 5, 0.528 g. sirup, was hydrolyzed, giving II and IV; a portion treated as in fraction 2 gave VI, VII, and VIII. Fraction 6, 0.65 g., contained II and IV. Methylation of I 6 times with (Me)2-SO4-NaOH, 5 times with MeI-Ag2O, hydrolysis with 2N H2SO1 at room temperature for 10 days and at 100° for 20 hrs., and separation on cellulose gave VI, VIII, 3-O-methyl-L-rhamnose (IX), m. 115°, a trace fraction, and a mixture of Ba salts which were treated as above and chromatographed, giving 2,3,4-tri-O-methyl-D-glucose, VIII, IX, and 2,3-di-O-methyl-D-galactose, aniline derivative m. 154°. K. senegalensis gum showed [α]D16 124° (c 0.9, H2O); found: equivalent 412 (titration), sulfated ash 2.2, OMe 1.2%, and containing the same sugar residues as the above gum but the proportions of uronic and III are different. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Electric Literature of C6H14O6).
(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Electric Literature of C6H14O6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts