One-pot synthesis of chiral alcohols from alkynes by CF3SO3H/ruthenium tandem catalysis was written by Liu, Huan;Liu, Sensheng;Zhou, Haifeng;Liu, Qixing;Wang, Chunqin. And the article was included in RSC Advances in 2018.Computed Properties of C8H9FO This article mentions the following:
A practical one-pot synthesis of chiral alcs. from readily available alkynes via tandem catalysis by the combination of CF3SO3H and a fluorinated chiral diamine Ru(II) complex in aqueous CF3CH2OH was described. Very interestingly, the combination of fluorinated catalysts and solvent exhibited a pos. fluorine effect on the reactivity and enantioselectivity. A range of chiral alcs. with wide functional group tolerance was obtained in high yield and excellent stereoselectivity under simple and mild conditions. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Computed Properties of C8H9FO).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Computed Properties of C8H9FO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts