Chiral Recognition and Separation by Chirality-Enriched Metal-Organic Frameworks was written by Das, Saikat;Xu, Shixian;Ben, Teng;Qiu, Shilun. And the article was included in Angewandte Chemie, International Edition in 2018.Recommanded Product: (R)-2-Aminobutan-1-ol This article mentions the following:
Endowed with chiral channels and pores, chiral metal-organic frameworks (MOF) are highly useful; however, their synthesis is a challenge since most chiral building blocks are expensive. Although MOF with induced chirality have been reported to avoid this shortcoming, no study providing evidence for the ee value of such MOF has yet been reported. This is the first study to describe the efficiency of chiral induction in MOF using inexpensive achiral building blocks and fully recoverable chiral dopants to control the handedness of racemic MOF. This method yielded chirality-enriched MOF with accessible pores. The ability of the materials to form host-guest complexes was probed with enantiomers of varying size and coordination and in solvents with varying polarity. Mixed-matrix membranes comprised of chirality-enriched MOF particles dispersed in a polymer matrix demonstrated a new chiral separation route. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Recommanded Product: (R)-2-Aminobutan-1-ol).
(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: (R)-2-Aminobutan-1-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts