Modelling and experimental studies on mass transport of multiple cryoprotective agents in articular cartilage was written by Yu, Xiaoyi;Zhang, Shaozhi;Chen, Guangming. And the article was included in Cryobiology in 2022.Related Products of 57-55-6 This article mentions the following:
Cartilage transplantation is an effective way to repair, reconstruct, and replace damaged articular cartilage (AC) but its use is limited by the inability to preserve AC for long periods of time. Vitrification is an ideal choice for long-term storage of AC, and multiple cryoprotective agents (CPAs) with high concentration are usually used. To obtain high cell viability, chondrocytes at all locations inside AC should be protected properly by the CPAs during cooling and rewarming. Hence, it is important to know the mass transport properties of multiple CPAs as they synergistically infiltrate AC. In this study, a math. model to describe the mass transport behavior of multiple CPAs in AC was developed based on the mixture-averaged diffusion model. In addition, a methodol. for the simultaneous determination of DMSO, glycerol, ethylene glycol, and propylene glycol by carbon-13 NMR was established. The model is applicable for predicting single- and multiple-CPA permeation into AC, and its accuracy was verified by a massive exptl. dataset. Simulation results showed reverse diffusion in the multiple-CPA permeation process, which was not found in the single-CPA permeation process. This curious phenomenon shows the sharp contrast between the diffusion behavior of a binary mixture and a multicomponent mixture In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Related Products of 57-55-6).
1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Related Products of 57-55-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts