1,2-Silylpyridylation Reaction of Aryl Alkenes with Silylboronate was written by Gao, Liuzhou;Liu, Xueting;Li, Guoao;Chen, Shengda;Cao, Jia;Wang, Guoqiang;Li, Shuhua. And the article was included in Organic Letters in 2022.Synthetic Route of C10H20O This article mentions the following:
A metal-free silyl-pyridylation of alkenes using silyl boronates and B2pin2 through a pyridine-mediated B-interelement activation was demonstrated, which provides a practical strategy for a variety of C4-silylalkylated pyridines. DFT calculations and control experiments show that the reaction proceeds through a silyl radical addition/radical-radical coupling sequence. This protocol features a broad substrate scope and excellent functional group compatibility, and thus it showcases great potential in the late-stage modification of bioactive mols. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Synthetic Route of C10H20O).
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Synthetic Route of C10H20O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts