LC-QTOF MS screening of more than 1000 licit and illicit drugs and their metabolites in wastewater and surface waters from the area of Bogota, Colombia was written by Hernandez, Felix;Ibanez, Maria;Botero-Coy, Ana-Maria;Bade, Richard;Bustos-Lopez, Martha Cristina;Rincon, Javier;Moncayo, Alejandro;Bijlsma, Lubertus. And the article was included in Analytical and Bioanalytical Chemistry in 2015.Recommanded Product: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid This article mentions the following:
A large screening of ∼1000 emerging contaminants, focused on licit and illicit drugs and their metabolites, has been made in urban wastewaters (both influent and effluent) and surface waters from the area of Bogota, Colombia. After a simple generic solid-phase extraction (SPE) step with Oasis hydrophilic-lipophilic balanced (HLB) cartridges, analyses were made by ultra HPLC coupled to quadrupole time-of-flight mass spectrometry (UHPLC-QTOF MS) under MSE mode (sequential acquisition of mass spectra at low energy (LE) and high collision energy (HE)). Accurate mass measurements and the information provided by MSE on the presence of the (de)protonated mol. and fragment ions allowed the reliable identification of the compounds detected, even without reference standards being available in some cases (tentative identification). The compounds most frequently found were acetaminophen/paracetamol, carbamazepine and its dihydro-dihydroxylated metabolite, clarithromycin, diclofenac, ibuprofen, gemfibrozil, lincomycin, losartan, valsartan, the 2 metabolites of metamizole (4-acetamido-antipyrine and 4-formylamino-antipyrine), sucralose, and cocaine and its main metabolite benzoylecgonine. Caffeine, the sweetener saccharin, and 2 hydroxylated metabolites of losartan were tentatively identified in almost all samples analyzed. Pharmaceutical lidocaine was tentatively identified and subsequently confirmed with reference standard For the 1st time, a general overview of the occurrence of drugs and their metabolites in the aquatic environment of Colombia has been reported. In the near future, target methodologies, typically based on liquid chromatog. coupled to tandem mass spectrometry (LC-MS/MS), will need to be set up for accurate and sensitive quantification of the contaminants selected on the basis on the information provided here. In the experiment, the researchers used many compounds, for example, 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6Recommanded Product: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid).
2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts