Cineole. XI. Action of aqueous sulfuric acid solution on cineole was written by Matsuura, Tamon;Furukawa, Tohru. And the article was included in Journal of Science of the Hiroshima University, Series A: Mathematics, Physics, Chemistry in 1955.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:
1,8-Cineole (I) was heated with 21% H2SO4 solution at 70° under agitation, the reaction time being 33, 15, and 3 h. In the case of the reaction time of 33 h., the reaction product was a mixture of p-cymene (II) (large amount) and α-terpinene (III) (small amount). In the case of 15 h., the constituents in the reaction product were: II, 28%; III, 8%; dl-α-terpineol (IV), 5%; and terpin hydrate (V), trace (59% of I remained unreacted in the oily product). In the case of 3 h. the oily product contained: I 93%; IV, 6%; unsaturated hydrocarbon, 1%; V, trace. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).
rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts