Hybrid polymeric systems of mesoporous silica/hydroxyapatite nanoparticles applied as antitumor drug delivery platform was written by dos Apostolos, Rafaela C. R.;Andrade, Gracielle F.;da Silva, Wellington M.;de Assis Gomes, Dawidson;de Miranda, Marcelo C.;de Sousa, Edesia M. B.. And the article was included in International Journal of Applied Ceramic Technology in 2019.Recommanded Product: 109-17-1 This article mentions the following:
In this study, we report the production of a mesoporous silica/hydroxyapatite-based nanocomposite containing copper (Cu) functionalized with methacrylic acid (MAA), a pH-sensitive polymer. The functionalization of the nanoparticles surface was performed using the microwave method in order to anchor the crosslinking tetraethylene glycol dimethacrylate (TEGDMA), onto the nanoparticles surface followed by MAA polymerization The materials were characterized by XRD, XRF spectroscopy, scanning and transmission electron microscopy, Fourier transform IR spectroscopy, thermal anal., zeta potential, and elemental anal. Studies of the incorporation and release of the antitumor methotrexate drug were performed in order to evaluate the potential use of these drug carrier systems in cancer therapy. Moreover, the in vitro cytotoxicity of the samples in fibroblast and SAOS-2 cells was investigated, and the activity of the adipose-derived stem cell alk. phosphatase on nanocomposites was studied by in vitro assays. The results indicate that the Cu-containing nanocomposites can be easily produced and that these compositions have beneficial effects in stem cells, maintaining cell viability, and allowing alk. phosphatase expression. In conclusion, data from this work show that the nanocomposites obtained have adequate characteristic to be used as drug delivery platform. Furthermore, the biomaterial is a promising structure for treatment of bone tumor. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Recommanded Product: 109-17-1).
((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 109-17-1
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts