Peng, Hui published the artcileTherapeutic effect of hemabate on preventing and treating bleeding in cesarean section or post-operation of high-risk parturient women, Application of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Yixue Linchuang Yanjiu (2009), 26(7), 1335-1336, database is CAplus.
The aim of this paper is to investigate therapeutic effect of hemabate on preventing and treating bleeding in cesarean section or post-operation of high-risk parturient women, and its safety. 60 High-risk parturient women were divided into two groups: hemabate group (A group with 30 cases)and oxytocin+methyl carboprost suppository group (B group with 30 cases). The bleeding amount was recorded during operation and 24h post- operation. Bleeding incidence rate in group B was significantly higher than that in group A (16.7 vs 6.67%). The bleeding amounts during operation and 24h post-operation were 441.57±252.03 mL and 651.26±308.24 mL in B group, while those in group A were 317.31±162.47 mL and 512.26±251.54 mL, resp., with significant difference between the two groups (P<0.05). Hemabate can effectively reduce bleeding amount in cesarean section or post-operation of high-risk parturient women and has advantages of safety, high performance, quickness and convenience.
Yixue Linchuang Yanjiu published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Application of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.
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