Zhu, Ya-rui published the artcileEffects of ambroxol hydrochloride combined with pulmicorin on changes of airway inflammation and allergic reaction EOS, ECP and IL-4 indexes in patients with bronchial asthma, Formula: C13H19Br2ClN2O, the publication is Xiandai Zhenduan Yu Zhiliao (2021), 32(5), 707-708, database is CAplus.
Objective: To investigate the effect of ambroxol hydrochloride combined with pulmicorin on airway inflammation and the changes of EOS, ECP and IL-4 indexes in patients with bronchial asthma. Methods: A total of 60 patients with bronchial asthma who were admitted to our hospital from Feb. 2019 to Dec. 2019 were selected and divided into a control group and an exptl. group with 30 cases in each group according to the method of tossing a coin. The control group was given routine treatment, and the exptl. group was given ambroxol hydrochloride combined with pulmicoride on this basis. The levels of eosinophils (EOS), eosinophil cationic protein (ECP), interleukin-4 (IL-4) and adverse reactions were observed in the two groups. Results: Before treatment, there was no significant difference in the levels of IL-4, ECP and EOS between the two groups (P>0.05). After treatment, the levels of IL-4, ECP and EOS in the two groups were lower than those before treatment, and the exptl. group was significantly lower than the control group (P<0.05). The incidence of adverse reactions in the exptl. group was significantly lower than that in the control group (P<0.05). Conclusion: Ambroxol hydrochloride combined with pulmicoride has pos. effect on airway inflammation and allergic reaction EOS, ECP and IL-4 levels in patients with bronchial asthma, with high safety, which is worthy of clin. application.
Xiandai Zhenduan Yu Zhiliao published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C38H74Cl2N2O4, Formula: C13H19Br2ClN2O.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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