Mirheydari, Seyyedeh Narjes published the artcileComparison of models for correlation of drug solubility in ethanol + water binary mixtures, Synthetic Route of 64519-82-0, the main research area is ethanol water binary mixture drug solubility computational model.
The ability of a number of common models for correlating the collected solubility data of drugs in ethanol + water mixtures (the number of data sets is 43) was tested. The selected models are classified within three groups, (1) λ-h, van’t Hoff and Apelblat models with temperature dependency, and modified Wilson with solvent composition dependency, (2) Jouyban-Acree, Jouyban-Acree-van’t Hoff and Jouyban-Acree-Apelblat (linear models) and NRTL, Wilson and UNIQUAC (nonlinear models) with both temperature and solvent composition dependencies, (3) UNIFAC, Yalkowsky, log-linear model of Yalkowsky, Jouyban-Acree-Abraham and Jouyban-Acree-Hansen predictive models. Of the models in group 1, the Apelblat model has the lowest overall %ARD and Jouyban-Acree-van’t Hoff and Jouyban-Acree-Apelblat models in group 2 performed best in correlations. Moreover, predictions using Jouyban-Acree-Abraham and Jouyban-Acree-Hansen models in group 3 have the lowest %ARDs in this group.
Journal of Solution Chemistry published new progress about Binary mixtures. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Synthetic Route of 64519-82-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts