Koremura, Mitsunobu published the artcileRelation between chemical structure and antimicrobial and insecticidal activities in organonitro compounds. I. Nitroalcohol derivatives, Related Products of alcohols-buliding-blocks, the publication is Takamine Kenkyusho Nenpo (1961), 198-204, database is CAplus.
Compounds (23) including nitroparaffins, nitroalkyl alcs., dinitroparaffins, nitro Ph alcs., ω-nitroacetophenone, and diphenylnitroethane were synthesized and tested for their biol. activities. Most of the alkyl nitro compounds except dinitroparaffins were inactive against plant pathogens and insects, whereas among the α-phenyl-β-nitro alcs. tested, 1-phenyl-2-nitroethanol had high antimicrobial activities against plant pathogens such as Xanthomonas oryzae and Glomerella cingulata and had insecticidal activity against housefly. This tendency applied similarly to the ω-nitro-acetophenone derivatives, where insecticidal activity was lost. The biol. activities of Ph nitro compounds were very low except 1-phenyl-2-nitroethanol, which indicated a possible effect of the partition coefficient of the compound between H2O and lipid on the biol. activity. It was presumed that the presence of the Ph radical was necessary for antimicrobial and insecticidal activities of the β-nitro compounds
Takamine Kenkyusho Nenpo published new progress about 528594-30-1. 528594-30-1 belongs to alcohols-buliding-blocks, auxiliary class Nitro Compound,Benzene,Phenol,Ether, name is 2-Methoxy-4-(2-nitroethyl)phenol, and the molecular formula is C9H11NO4, Related Products of alcohols-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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