West, F. G.’s team published research in Journal of Organic Chemistry in 59 | CAS: 101-98-4

Journal of Organic Chemistry published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C17H16O2, Synthetic Route of 101-98-4.

West, F. G. published the artcileApplications of Stevens [1,2]-Shifts of Cyclic Ammonium Ylides. A Route to Morpholin-2-ones, Synthetic Route of 101-98-4, the publication is Journal of Organic Chemistry (1994), 59(20), 6051-6, database is CAplus.

2-(N,N-Dialkylamino)ethyl diazoacetoacetates I (R1 = benzyl, alkyl, etc.; R2 = Me, benzyl) were prepared in two steps from ethanolamines. When heated in the presence of catalytic Cu, the substrates cleanly formed morpholinones II (same R1, R2), presumably via the intermediacy of copper carbenoids and cyclic ammonium ylides. In most cases involving benzylic or allylic migrating groups, ylide [1,2]-shift occurred in good yield (55-80%). Simple alkyl groups failed to undergo the rearrangement, with the exception of a tert-Bu substituted compound, which furnished morpholinone II (R1 = tert-Bu, R2 = Me) in 10% yield.

Journal of Organic Chemistry published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C17H16O2, Synthetic Route of 101-98-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts