Zhu, Yazhi published the artcileDirectly photopatterning of polycaprolactone-derived photocured resin by UV-initiated thiol-ene “”click”” reaction: Enhanced mechanical property and excellent biocompatibility, Synthetic Route of 7575-23-7, the main research area is biomedical polycaprolactone photocured resin UV photopatterning property biocompatibility.
This paper reports a novel routine for the fabrication of a polycaprolactone-derived (PCL-derived) photocured material crosslinked by pentaerythritol tetra (PETMP) with enhanced mech. property and excellent biocompatibility. The photocured material is crosslinked via UV irradiation through thiol-ene “”click”” chem. The main novelty of this technique is the facile fabrication of high-resolution patterns (â?μm) using photolithog., and without adding photo-initiators. The photocured material is studied regarding to its thermal property, mech. property and cytocompatibility. DSC and DMA suggest that the flexibility and toughness of PCL-derived photocured material have improved. Accordingly, the PCL-derived photocured material achieves enhanced mech. property (with the increase of PCL segment content from 0 to 38.0%, the photocured samples monotonically increased their breaking strength from 0.62 to 3.10 MPa and Young’s modulus from 1.39 to 9.22 MPa). Due to the incorporation of the PCL-derived copolymer, the material shows excellent affinity to cells, which is demonstrated by the cell proliferation and release of LDH. The hemolysis ratio of PCL-derived photocured materials is all <5%, while the PEGDA photocured material is â?7%. It can also be observed that PCL-derived photocured material will improve the biocompatibility and reduce biotoxicity compared with PEGDA. This facile route for synthesis of biocompatible photocured resin with micrometer-resolute patterns has a good impact in bioengineering and biomedical fields. Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Absorption. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Synthetic Route of 7575-23-7.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts