Reddy, A. B. published the artcileTriazino-caffeine Derivatives by Intramolecular Cyclization: Synthesis, Characterization and Antimicrobial Studies, Category: alcohols-buliding-blocks, the publication is Letters in Organic Chemistry (2018), 15(6), 540-545, database is CAplus.
In the present study, a new class of triazino-caffeine derivatives with good antimicrobial activities is reported. Eight new triazino-caffeine derivatives were synthesized via Mitsunobu reaction, followed by intramol. cyclization. Their chem. structures were established on the basis of elemental anal., IR, 1H NMR, mass spectral data as well as through an alternate synthetic route. The compounds were also screened for their antimicrobial activities, among them, compounds I (R = Me, H) showed good inhibitory potentials, indicating the importance of the morpholine moiety in enhancing antimicrobial activity. Therefore, it is concluded that the triazino-caffeine derivatives developed, show encouraging potentials in their medicinal applications.
Letters in Organic Chemistry published new progress about 622-40-2. 622-40-2 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Alcohol, name is 2-Morpholinoethanol, and the molecular formula is C6H13NO2, Category: alcohols-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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