Wang, Rui-jiao published the artcileStudy on effect of oxytocin combined with carboprost tromethamine in preventing postpartum hemorrhage in high-risk women, Category: alcohols-buliding-blocks, the publication is Zhongguo Fuyou Baojian (2016), 31(15), 3033-3035, database is CAplus.
Objective: To analyze the preventive effect of the combination of carboprost tromethamine and oxytocin on postpartum hemorrhage in cesarean section of high-risk women, and observe the occurrence of adverse reactions after maternal medication. Methods: A total of 120 high-risk pregnant women who were scheduled for cesarean delivery at the Obstetrics Department of Liaobu Hospital in Dongguan City were collected, and randomly divided into 3 groups. 40 cases in group A, who were given oxytocin alone. 40 patients in group B were treated with oxytocin combined with carboprost methylate suppository. 40 patients in group C were given oxytocin combined with carboprost tromethamine. The intraoperative and postoperative bleeding volume, postpartum hemorrhage, treatment and adverse reactions of the three groups were compared. Results: The intraoperative and postoperative 2 h bleeding volume of group B and group C were significantly lower than that of group A (P < 0.05), among which the difference of group C was more significant. The bleeding volume in group C was significantly lower than that in group A and group B at 2-24 h after operation (P < 0.05). The incidence of postpartum hemorrhage, blood transfusion rate, and treatment rate of other hemostatic measures in group B and group C were significantly lower than those in group A (P < 0.05). Conclusion: The combination of carboprost tromethamine and oxytocin can effectively reduce the amount of postpartum hemorrhage and the incidence of postpartum hemorrhage in high-risk women, and it is safe and worthy of further promotion.
Zhongguo Fuyou Baojian published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C11H19N, Category: alcohols-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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