Krasniqi, Besir published the artcileGeneral Transition Metal-Free Synthesis of NH-Pyrroles from Secondary Alcohols and 2-Aminoalcohols, Name: 2-Aminobutan-1-ol, the publication is Journal of Organic Chemistry (2019), 84(9), 5027-5034, database is CAplus and MEDLINE.
A novel, transition metal-free and one-pot methodol. to synthesize various substituted NH-pyrroles from readily available building blocks such as secondary alcs. and 2-aminoalcs. is described. The process is based on the venerable Oppenauer-Woodward oxidation, which uses benzophenone as an inexpensive reagent to achieve oxidation of secondary alcs. under mild condition to ketones, further in situ condensation with aminoalc., and oxidative cyclization to the target pyrrole ring. The reaction occurs under basic conditions, and features a broad substrate scope combined with very good tolerance for sensitive functional groups. This method can be used to synthesize various substituted pyrroles useful as a starting material for broad applications.
Journal of Organic Chemistry published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Name: 2-Aminobutan-1-ol.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts