Bruusgaard-Mouritsen, Maria A. published the artcileFacial contact dermatitis caused by cosmetic-relevant allergens, Synthetic Route of 70445-33-9, the publication is Contact Dermatitis (2021), 85(6), 650-659, database is CAplus and MEDLINE.
Facial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge. To investigate characteristics of patients with facial dermatitis (FD) between 2010 and 2019 including patch test results from cosmetic-related allergens and a new test series with cosmetic-relevant natural ingredients (CRNIs). This is a retrospective study analyzing demographics, clin. characteristics according to MOAHLFA index (male; occupation; atopic dermatitis; hand; leg; face; age ≥ 40 years), and patch test results to 27 cosmetic-relevant allergens in FD patients. A prospective study evaluating a screening test series with CRNIs in consecutive FD patients for 1 yr was also conducted. These patients received a questionnaire for collecting extra characteristics (eg, concerning quality of life). Of 8740 tested patients, 2292 (26.2%) had FD. Of these, 30.6% had cosmetic-induced FD. The most common cosmetic-related allergens were fragrances and preservatives. The most common patch test-pos. CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test-pos. CRNIs, however, without any relation to the use of cosmetic products. FD affected nearly all patients′ quality of life and caused limitations to their daily life. Updated management and quick diagnosis of FD is important to avoid neg. impact on patients′ quality of life.
Contact Dermatitis published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Synthetic Route of 70445-33-9.
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