Katiyar, R. D. published the artcileThiabendazole as an anthelmintic of outstanding efficiency, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Indian Veterinary Journal (1964), 41(12), 803-9, database is CAplus.
Four trials are described in which thiabendazole [2-(4-thiazolyl)benzimidazole] (I) efficiency is tested against nematodes. Frantin (bephenium hydroxynaphthoate) (II), Promintic (Methrydine) (III), and phenothiazine (IV) were used as comparisons. Lambs naturally parasitized with Haemonchus, Trichostrongyles, Ostertagia, Nematodirus, Oesophagostomum, Cooperia, and Bunostomum spp. were treated with I (50 mg./kg. body weight), II (4 g./lamb), III (200 mg./kg. body weight), IV (600 mg./kg.) and no treatment. The reductions in egg counts were 95.7, 82.1, 78.7, 76.2, and 39.2%, resp. Against individual nematode species in sheep, I was 85-100% effective. It was 97.7% effective against nematodes causing gastroenteritis in crossbred Angora kids, while IV was only 76.5% effective. Romney Marsh rams with a heavy infestation of Strongloides papillosus were treated with IV with no effect, while treatment with I reduced the ova count by 91-95% over 15 days. In all trials, treatment with I increased the body weight
Indian Veterinary Journal published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.
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