Kadirvel, Manikandan published the artcileInhibition of quorum sensing and biofilm formation in Vibrio harveyi by 4-fluoro-DPD; a novel potent inhibitor of AI-2 signalling, Product Details of C3H6O2, the publication is Chemical Communications (Cambridge, United Kingdom) (2014), 50(39), 5000-5002, database is CAplus and MEDLINE.
(S)-4,5-Dihydroxypentane-2,3-dione [(S)-DPD] is a precursor for AI-2, a quorum sensing signalling mol. for inter- and intra-species bacterial communication. The synthesis of its fluoro-analog, 4-fluoro-5-hydroxypentane-2,3-dione (4-fluoro-DPD) is reported. An intermediate in this route also enables a new, shorter synthesis of the native (S)-DPD. 4-Fluoro-DPD completely inhibited bioluminescence and bacterial growth of Vibrio harveyi BB170 strain at 12.5 μM and 100 μM, resp.
Chemical Communications (Cambridge, United Kingdom) published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Product Details of C3H6O2.
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