Blaser, Hans-Ulrich’s team published research in Journal of Organic Chemistry in 68 | CAS: 27292-49-5

Journal of Organic Chemistry published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C10H13NO2, HPLC of Formula: 27292-49-5.

Blaser, Hans-Ulrich published the artcileNo Stirring Necessary: Parallel Carbonylation of Aryl Halides with CO and Various Alcohols under Pressure, HPLC of Formula: 27292-49-5, the publication is Journal of Organic Chemistry (2003), 68(9), 3725-3728, database is CAplus and MEDLINE.

The parallel carbonylation of aryl and heteroaryl halides R1X (R1 = 4-MeCOC6H4, X = Br; R1 = 2-pyridyl, X = Cl) with 6-25 bar of CO in 1-mL vials in a standard autoclave in the presence of an O-nucleophile R2OH (R2 = Bu, PhCH2, cyclopentyl, etc.) to give the corresponding esters R1CO2R2 was investigated. With 2-chloropyridine as a model substrate, 102 different O-nucleophiles (primary and secondary alcs., phenols) were studied. No inertization during the loading was necessary. Fifty esters (43 new, yield up to 60%) were isolated and characterized. Ether, ester, ketone, and sometimes even olefin functionalities were usually tolerated. The new method is suitable for screening and small scale synthesis.

Journal of Organic Chemistry published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C10H13NO2, HPLC of Formula: 27292-49-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts